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Antifungal Potential of Synthetic Peptides against Cryptococcus neoformans: Mechanism of Action Studies Reveal Synthetic Peptides Induce Membrane–Pore Formation, DNA Degradation, and Apoptosis
Cryptococcus neoformans is a human-pathogenic yeast responsible for pneumonia and meningitis, mainly in patients immunocompromised. Infections caused by C. neoformans are a global health concern. Synthetic antimicrobial peptides (SAMPs) have emerged as alternative molecules to cope with fungal infec...
Autores principales: | Aguiar, Tawanny K. B., Neto, Nilton A. S., Freitas, Cleverson D. T., Silva, Ayrles F. B., Bezerra, Leandro P., Malveira, Ellen A., Branco, Levi A. C., Mesquita, Felipe P., Goldman, Gustavo H., Alencar, Luciana M. R., Oliveira, Jose T. A., Santos-Oliveira, Ralph, Souza, Pedro F. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416200/ https://www.ncbi.nlm.nih.gov/pubmed/36015304 http://dx.doi.org/10.3390/pharmaceutics14081678 |
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