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Antifungal Potential of Synthetic Peptides against Cryptococcus neoformans: Mechanism of Action Studies Reveal Synthetic Peptides Induce Membrane–Pore Formation, DNA Degradation, and Apoptosis

Cryptococcus neoformans is a human-pathogenic yeast responsible for pneumonia and meningitis, mainly in patients immunocompromised. Infections caused by C. neoformans are a global health concern. Synthetic antimicrobial peptides (SAMPs) have emerged as alternative molecules to cope with fungal infec...

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Detalles Bibliográficos
Autores principales: Aguiar, Tawanny K. B., Neto, Nilton A. S., Freitas, Cleverson D. T., Silva, Ayrles F. B., Bezerra, Leandro P., Malveira, Ellen A., Branco, Levi A. C., Mesquita, Felipe P., Goldman, Gustavo H., Alencar, Luciana M. R., Oliveira, Jose T. A., Santos-Oliveira, Ralph, Souza, Pedro F. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416200/
https://www.ncbi.nlm.nih.gov/pubmed/36015304
http://dx.doi.org/10.3390/pharmaceutics14081678

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