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The Bile Acid Membrane Receptor TGR5 in Cancer: Friend or Foe?

The G-protein-coupled bile acid receptor, Gpbar1 or TGR5, is characterized as a membrane receptor specifically activated by bile acids. A series of evidence shows that TGR5 induces protein kinase B (AKT), nuclear factor kappa-B (NF-κB), extracellular regulated protein kinases (ERK1/2), signal transd...

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Detalles Bibliográficos
Autores principales: Qi, Youchao, Duan, Guozhen, Wei, Dengbang, Zhao, Chengzhou, Ma, Yonggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416356/
https://www.ncbi.nlm.nih.gov/pubmed/36014536
http://dx.doi.org/10.3390/molecules27165292