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The Cellular and Molecular Immunotherapy in Prostate Cancer

In recent history, immunotherapy has become a viable cancer therapeutic option. However, over many years, its tenets have changed, and it now comprises a range of cancer-focused immunotherapies. Clinical trials are currently looking into monotherapies or combinations of medicines that include immune...

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Autores principales: Mukherjee, Anirban Goutam, Wanjari, Uddesh Ramesh, Prabakaran, D. S., Ganesan, Raja, Renu, Kaviyarasi, Dey, Abhijit, Vellingiri, Balachandar, Kandasamy, Sabariswaran, Ramesh, Thiyagarajan, Gopalakrishnan, Abilash Valsala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416492/
https://www.ncbi.nlm.nih.gov/pubmed/36016257
http://dx.doi.org/10.3390/vaccines10081370
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author Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Prabakaran, D. S.
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Kandasamy, Sabariswaran
Ramesh, Thiyagarajan
Gopalakrishnan, Abilash Valsala
author_facet Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Prabakaran, D. S.
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Kandasamy, Sabariswaran
Ramesh, Thiyagarajan
Gopalakrishnan, Abilash Valsala
author_sort Mukherjee, Anirban Goutam
collection PubMed
description In recent history, immunotherapy has become a viable cancer therapeutic option. However, over many years, its tenets have changed, and it now comprises a range of cancer-focused immunotherapies. Clinical trials are currently looking into monotherapies or combinations of medicines that include immune checkpoint inhibitors (ICI), CART cells, DNA vaccines targeting viruses, and adoptive cellular therapy. According to ongoing studies, the discipline should progress by incorporating patient-tailored immunotherapy, immune checkpoint blockers, other immunotherapeutic medications, hormone therapy, radiotherapy, and chemotherapy. Despite significantly increasing morbidity, immunotherapy can intensify the therapeutic effect and enhance immune responses. The findings for the immunotherapy treatment of advanced prostate cancer (PCa) are compiled in this study, showing that is possible to investigate the current state of immunotherapy, covering new findings, PCa treatment techniques, and research perspectives in the field’s unceasing evolution.
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spelling pubmed-94164922022-08-27 The Cellular and Molecular Immunotherapy in Prostate Cancer Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Prabakaran, D. S. Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Kandasamy, Sabariswaran Ramesh, Thiyagarajan Gopalakrishnan, Abilash Valsala Vaccines (Basel) Review In recent history, immunotherapy has become a viable cancer therapeutic option. However, over many years, its tenets have changed, and it now comprises a range of cancer-focused immunotherapies. Clinical trials are currently looking into monotherapies or combinations of medicines that include immune checkpoint inhibitors (ICI), CART cells, DNA vaccines targeting viruses, and adoptive cellular therapy. According to ongoing studies, the discipline should progress by incorporating patient-tailored immunotherapy, immune checkpoint blockers, other immunotherapeutic medications, hormone therapy, radiotherapy, and chemotherapy. Despite significantly increasing morbidity, immunotherapy can intensify the therapeutic effect and enhance immune responses. The findings for the immunotherapy treatment of advanced prostate cancer (PCa) are compiled in this study, showing that is possible to investigate the current state of immunotherapy, covering new findings, PCa treatment techniques, and research perspectives in the field’s unceasing evolution. MDPI 2022-08-22 /pmc/articles/PMC9416492/ /pubmed/36016257 http://dx.doi.org/10.3390/vaccines10081370 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Prabakaran, D. S.
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Kandasamy, Sabariswaran
Ramesh, Thiyagarajan
Gopalakrishnan, Abilash Valsala
The Cellular and Molecular Immunotherapy in Prostate Cancer
title The Cellular and Molecular Immunotherapy in Prostate Cancer
title_full The Cellular and Molecular Immunotherapy in Prostate Cancer
title_fullStr The Cellular and Molecular Immunotherapy in Prostate Cancer
title_full_unstemmed The Cellular and Molecular Immunotherapy in Prostate Cancer
title_short The Cellular and Molecular Immunotherapy in Prostate Cancer
title_sort cellular and molecular immunotherapy in prostate cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416492/
https://www.ncbi.nlm.nih.gov/pubmed/36016257
http://dx.doi.org/10.3390/vaccines10081370
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