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Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid

The pivotal tryptophan (TRP) metabolite kynurenine is converted to several neuroactive compounds, including kynurenic acid (KYNA), which is elevated in the brain and cerebrospinal fluid of people with schizophrenia (SZ) and may contribute to cognitive abnormalities in patients. A small proportion of...

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Detalles Bibliográficos
Autores principales:	Sathyasaikumar, Korrapati V., Notarangelo, Francesca M., Kelly, Deanna L., Rowland, Laura M., Hare, Stephanie M., Chen, Shuo, Mo, Chen, Buchanan, Robert W., Schwarcz, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416551/ https://www.ncbi.nlm.nih.gov/pubmed/36015151 http://dx.doi.org/10.3390/ph15081003

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