Synthesis and In Silico Docking Study towards M-Pro of Novel Heterocyclic Compounds Derived from Pyrazolopyrimidinone as Putative SARS-CoV-2 Inhibitors

In addition to vaccines, antiviral drugs are essential in order to suppress COVID-19. Although some inhibitor candidates have been determined to target the SARS-CoV-2 protein, there is still an urgent need to continue researching novel inhibitors of the SARS-CoV-2 main protease ‘Omicron P132H’, a pr...

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Detalles Bibliográficos
Autores principales: Horchani, Mabrouk, Heise, Niels V., Csuk, René, Ben Jannet, Hichem, Harrath, Abdel Halim, Romdhane, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416631/
https://www.ncbi.nlm.nih.gov/pubmed/36014537
http://dx.doi.org/10.3390/molecules27165303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416631/
https://www.ncbi.nlm.nih.gov/pubmed/36014537
http://dx.doi.org/10.3390/molecules27165303

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