α-Lipoic Acid Protects against Cyclosporine A-Induced Hepatic Toxicity in Rats: Effect on Oxidative Stress, Inflammation, and Apoptosis

The clinical application of cyclosporine A (CsA) as an immunosuppressive agent is limited by its organ toxicity. We aimed to evaluate the effectiveness of α-lipoic acid against CsA-induced hepatotoxicity and to delineate the underlying molecular mechanisms. Male Wistar rats (n = 24, 8 per each group...

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Detalles Bibliográficos
Autores principales: El-Mancy, Eman M., Elsherbini, Dalia Mahmoud Abdelmonem, Al-Serwi, Rasha Hamed, El-Sherbiny, Mohamed, Ahmed Shaker, Gehan, Abdel-Moneim, Abdel-Moneim Hafez, Enan, Eman T., Elsherbiny, Nehal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416703/
https://www.ncbi.nlm.nih.gov/pubmed/36006121
http://dx.doi.org/10.3390/toxics10080442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416703/
https://www.ncbi.nlm.nih.gov/pubmed/36006121
http://dx.doi.org/10.3390/toxics10080442

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