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Inhibition of HSP90 Preserves Blood–Brain Barrier Integrity after Cortical Spreading Depression

Cortical spreading depression (CSD) is a pathophysiological mechanism underlying headache disorders, including migraine. Blood–brain barrier (BBB) permeability is increased during CSD. Recent papers have suggested that heat shock proteins (HSP) contribute to the integrity of the blood–brain barrier....

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Detalles Bibliográficos
Autores principales: Palomino, Seph M., Levine, Aidan A., Wahl, Jared, Liktor-Busa, Erika, Streicher, John M., Largent-Milnes, Tally M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416719/
https://www.ncbi.nlm.nih.gov/pubmed/36015292
http://dx.doi.org/10.3390/pharmaceutics14081665