Synthesis of Functionalized Azepines via Cu(I)-Catalyzed Tandem Amination/Cyclization Reaction of Fluorinated Allenynes

An efficient method for the selective preparation of trifluoromethyl-substituted azepin-2-carboxylates and their phosphorous analogues has been developed via Cu(I)-catalyzed tandem amination/cyclization reaction of functionalized allenynes with primary and secondary amines.

Detalles Bibliográficos
Autores principales: Philippova, Anna N., Vorobyeva, Daria V., Gribanov, Pavel S., Godovikov, Ivan A., Osipov, Sergey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416787/
https://www.ncbi.nlm.nih.gov/pubmed/36014436
http://dx.doi.org/10.3390/molecules27165195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416787/
https://www.ncbi.nlm.nih.gov/pubmed/36014436
http://dx.doi.org/10.3390/molecules27165195

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