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Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin
Integrins are ubiquitous cell-surface heterodimers that are exploited by pathogens and toxins, including leukotoxins that target β(2) integrins on phagocytes. The Bordetella adenylate cyclase toxin (ACT) uses the α(M)β(2) integrin as a receptor, but the structural basis for integrin binding and neut...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416875/ https://www.ncbi.nlm.nih.gov/pubmed/35977491 http://dx.doi.org/10.1016/j.celrep.2022.111196 |