TNF-α enhances sensory DRG neuron excitability through modulation of P2X3 receptors in an acute colitis model

Previous studies have demonstrated that acute colonic inflammation leads to an increase in dorsal root ganglia (DRG) neuronal excitability. However, the signaling elements implicated in this hyperexcitability have yet to be fully unraveled. Extracellular adenosine 5’-triphosphate (ATP) is a well-rec...

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Detalles Bibliográficos
Autores principales: Valdez-Morales, Eduardo E., Sánchez-Navarro, Carlos A., Reyes-Pavón, Diana, Barrios-Garcia, Tonatiuh, Ochoa-Cortes, Fernando, Barajas-Espinosa, Alma, Barragán-Iglesias, Paulino, Guerrero-Alba, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416886/
https://www.ncbi.nlm.nih.gov/pubmed/36032155
http://dx.doi.org/10.3389/fimmu.2022.872760

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