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Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations

The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media.

Detalles Bibliográficos
Autores principales: Hobson, James J., Curley, Paul, Savage, Alison C., Al-khouja, Amer, Siccardi, Marco, Flexner, Charles, Meyers, Caren Freel, Owen, Andrew, Rannard, Steve P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417103/
https://www.ncbi.nlm.nih.gov/pubmed/36134394
http://dx.doi.org/10.1039/c9na00529c
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author Hobson, James J.
Curley, Paul
Savage, Alison C.
Al-khouja, Amer
Siccardi, Marco
Flexner, Charles
Meyers, Caren Freel
Owen, Andrew
Rannard, Steve P.
author_facet Hobson, James J.
Curley, Paul
Savage, Alison C.
Al-khouja, Amer
Siccardi, Marco
Flexner, Charles
Meyers, Caren Freel
Owen, Andrew
Rannard, Steve P.
author_sort Hobson, James J.
collection PubMed
description The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media.
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spelling pubmed-94171032022-09-20 Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations Hobson, James J. Curley, Paul Savage, Alison C. Al-khouja, Amer Siccardi, Marco Flexner, Charles Meyers, Caren Freel Owen, Andrew Rannard, Steve P. Nanoscale Adv Chemistry The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media. RSC 2019-10-12 /pmc/articles/PMC9417103/ /pubmed/36134394 http://dx.doi.org/10.1039/c9na00529c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Hobson, James J.
Curley, Paul
Savage, Alison C.
Al-khouja, Amer
Siccardi, Marco
Flexner, Charles
Meyers, Caren Freel
Owen, Andrew
Rannard, Steve P.
Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations
title Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations
title_full Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations
title_fullStr Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations
title_full_unstemmed Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations
title_short Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations
title_sort anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417103/
https://www.ncbi.nlm.nih.gov/pubmed/36134394
http://dx.doi.org/10.1039/c9na00529c
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