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Frailty index, mortality, and length of stay in a geriatric short-stay unit in Guadeloupe

CONTEXT: The COVID-19 pandemic has placed a tremendous stress on healthcare systems and caused reorganization. As the pandemic intensifies, identifying the profile of patients with COVID-19 was primordial in order to predict negative outcomes and organize healthcare resources. Age is associated with...

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Autores principales: Vainqueur, Larissa, Simo-Tabue, Nadine, Villeneuve, Roxane, Dagonia, Dorice, Bhakkan-Mambir, Bernard, Mounsamy, Ludwig, Delacroix, Vaynome, Tabue-Teguo, Maturin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417108/
https://www.ncbi.nlm.nih.gov/pubmed/36035408
http://dx.doi.org/10.3389/fmed.2022.963687
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author Vainqueur, Larissa
Simo-Tabue, Nadine
Villeneuve, Roxane
Dagonia, Dorice
Bhakkan-Mambir, Bernard
Mounsamy, Ludwig
Delacroix, Vaynome
Tabue-Teguo, Maturin
author_facet Vainqueur, Larissa
Simo-Tabue, Nadine
Villeneuve, Roxane
Dagonia, Dorice
Bhakkan-Mambir, Bernard
Mounsamy, Ludwig
Delacroix, Vaynome
Tabue-Teguo, Maturin
author_sort Vainqueur, Larissa
collection PubMed
description CONTEXT: The COVID-19 pandemic has placed a tremendous stress on healthcare systems and caused reorganization. As the pandemic intensifies, identifying the profile of patients with COVID-19 was primordial in order to predict negative outcomes and organize healthcare resources. Age is associated with COVID-19’s mortality, but for obvious ethical reasons, chronological age cannot be the sole criterion for predicting negative outcomes. OBJECTIVE: The objective of this study was to determine the relationship between frailty index (FI) and length of hospital stay, and death in a non-COVID population of patients aged 75 years old and above. METHODS AND DESIGN: A retrospective, analytical, single-centered observational study was performed in the geriatric short-stay accommodation unit at Guadeloupe University Hospital. For this study, 158 patients who were at least 75 years old were recruited from November 2020 to May 2021. FI was calculated as the number of deficits in a participant divided by the total number of deficits considered (the cut-off of FI is.25 in outpatient). Multivariate logistics regression analyses were conducted to assess the association between frailty and death, and length of stay. RESULTS: The average age of the participants was 85.7 ± 6.74 with a range of 75–104. Twenty-four of the patients died during hospitalization. FI was only significantly associated with mortality even after adjustment for age and gender (HR 26.3, 95% CI 1.7–413.4, P = 0.021). The association was stronger in the highest tertile of the FI (age- and gender-adjusted HR 4.6, 95% CI 1.39–15.11, P = 0.01). There was no significant interaction between FI and length of stay. CONCLUSION: Our study shows an association between FI (in terms of age-related deficit accumulation) and mortality in a non-COVID geriatric short-stay unit in Guadeloupe. The FI seems to have a lower capacity to catch events such as length of stay in this very complex population. Further research studies have to be conducted for better understanding and investigation of our findings.
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spelling pubmed-94171082022-08-27 Frailty index, mortality, and length of stay in a geriatric short-stay unit in Guadeloupe Vainqueur, Larissa Simo-Tabue, Nadine Villeneuve, Roxane Dagonia, Dorice Bhakkan-Mambir, Bernard Mounsamy, Ludwig Delacroix, Vaynome Tabue-Teguo, Maturin Front Med (Lausanne) Medicine CONTEXT: The COVID-19 pandemic has placed a tremendous stress on healthcare systems and caused reorganization. As the pandemic intensifies, identifying the profile of patients with COVID-19 was primordial in order to predict negative outcomes and organize healthcare resources. Age is associated with COVID-19’s mortality, but for obvious ethical reasons, chronological age cannot be the sole criterion for predicting negative outcomes. OBJECTIVE: The objective of this study was to determine the relationship between frailty index (FI) and length of hospital stay, and death in a non-COVID population of patients aged 75 years old and above. METHODS AND DESIGN: A retrospective, analytical, single-centered observational study was performed in the geriatric short-stay accommodation unit at Guadeloupe University Hospital. For this study, 158 patients who were at least 75 years old were recruited from November 2020 to May 2021. FI was calculated as the number of deficits in a participant divided by the total number of deficits considered (the cut-off of FI is.25 in outpatient). Multivariate logistics regression analyses were conducted to assess the association between frailty and death, and length of stay. RESULTS: The average age of the participants was 85.7 ± 6.74 with a range of 75–104. Twenty-four of the patients died during hospitalization. FI was only significantly associated with mortality even after adjustment for age and gender (HR 26.3, 95% CI 1.7–413.4, P = 0.021). The association was stronger in the highest tertile of the FI (age- and gender-adjusted HR 4.6, 95% CI 1.39–15.11, P = 0.01). There was no significant interaction between FI and length of stay. CONCLUSION: Our study shows an association between FI (in terms of age-related deficit accumulation) and mortality in a non-COVID geriatric short-stay unit in Guadeloupe. The FI seems to have a lower capacity to catch events such as length of stay in this very complex population. Further research studies have to be conducted for better understanding and investigation of our findings. Frontiers Media S.A. 2022-08-12 /pmc/articles/PMC9417108/ /pubmed/36035408 http://dx.doi.org/10.3389/fmed.2022.963687 Text en Copyright © 2022 Vainqueur, Simo-Tabue, Villeneuve, Dagonia, Bhakkan-Mambir, Mounsamy, Delacroix and Tabue-Teguo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Vainqueur, Larissa
Simo-Tabue, Nadine
Villeneuve, Roxane
Dagonia, Dorice
Bhakkan-Mambir, Bernard
Mounsamy, Ludwig
Delacroix, Vaynome
Tabue-Teguo, Maturin
Frailty index, mortality, and length of stay in a geriatric short-stay unit in Guadeloupe
title Frailty index, mortality, and length of stay in a geriatric short-stay unit in Guadeloupe
title_full Frailty index, mortality, and length of stay in a geriatric short-stay unit in Guadeloupe
title_fullStr Frailty index, mortality, and length of stay in a geriatric short-stay unit in Guadeloupe
title_full_unstemmed Frailty index, mortality, and length of stay in a geriatric short-stay unit in Guadeloupe
title_short Frailty index, mortality, and length of stay in a geriatric short-stay unit in Guadeloupe
title_sort frailty index, mortality, and length of stay in a geriatric short-stay unit in guadeloupe
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417108/
https://www.ncbi.nlm.nih.gov/pubmed/36035408
http://dx.doi.org/10.3389/fmed.2022.963687
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