Safety and Pharmacokinetics of Monoclonal Antibodies VRC07-523LS and PGT121 Administered Subcutaneously for Human Immunodeficiency Virus Prevention

BACKGROUND: Effective, long-acting prevention approaches are needed to reduce human immunodeficiency virus (HIV) incidence. We evaluated the safety and pharmacokinetics of VRC07-523LS and PGT121 administered subcutaneously alone and in combination as passive immunization for young women in South Afr...

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Detalles Bibliográficos
Autores principales: Mahomed, Sharana, Garrett, Nigel, Capparelli, Edmund V, Osman, Farzana, Harkoo, Ishana, Yende-Zuma, Nonhlanhla, Gengiah, Tanuja N, Archary, Derseree, Samsunder, Natasha, Baxter, Cheryl, Mkhize, Nonhlanhla N, Modise, Tandile, Carlton, Kevin, McDermott, Adrian, Moore, Penny L, Karim, Quarraisha Abdool, Barouch, Dan H, Fast, Patricia E, Mascola, John R, Ledgerwood, Julie E, Morris, Lynn, Abdool Karim, Salim S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417124/
https://www.ncbi.nlm.nih.gov/pubmed/35134995
http://dx.doi.org/10.1093/infdis/jiac041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417124/
https://www.ncbi.nlm.nih.gov/pubmed/35134995
http://dx.doi.org/10.1093/infdis/jiac041

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