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Prevention of Respiratory Syncytial Virus Infection in Healthy Adults by a Single Immunization of Ad26.RSV.preF in a Human Challenge Study

BACKGROUND: Respiratory syncytial virus (RSV) is a significant cause of severe lower respiratory tract disease in children and older adults, but has no approved vaccine. This study assessed the potential of Ad26.RSV.preF to protect against RSV infection and disease in an RSV human challenge model. M...

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Detalles Bibliográficos
Autores principales: Sadoff, Jerald, De Paepe, Els, DeVincenzo, John, Gymnopoulou, Efi, Menten, Joris, Murray, Bryan, Rosemary Bastian, Arangassery, Vandebosch, An, Haazen, Wouter, Noulin, Nicolas, Comeaux, Christy, Heijnen, Esther, Eze, Kingsley, Gilbert, Anthony, Lambkin-Williams, Rob, Schuitemaker, Hanneke, Callendret, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417128/
https://www.ncbi.nlm.nih.gov/pubmed/33400792
http://dx.doi.org/10.1093/infdis/jiab003