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Regulation of PD-L1 through direct binding of cholesterol to CRAC motifs

Cholesterol, an essential molecule for cell structure, function, and viability, plays crucial roles in the development, progression, and survival of cancer cells. Earlier studies have shown that cholesterol-lowering drugs can inhibit the high expression of programmed-death ligand 1 (PD-L1) that cont...

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Detalles Bibliográficos
Autores principales:	Wang, Qian, Cao, Yunlei, Shen, Lijuan, Xiao, Taoran, Cao, Ruiyu, Wei, Shukun, Tang, Meng, Du, Lingyu, Wu, Hongyi, Wu, Bin, Yu, Yang, Wang, Shuqing, Wen, Maorong, OuYang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417176/ https://www.ncbi.nlm.nih.gov/pubmed/36026448 http://dx.doi.org/10.1126/sciadv.abq4722

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