Cargando…

Accurate inference of genome-wide spatial expression with iSpatial

Spatially resolved transcriptomic analyses can reveal molecular insights underlying tissue structure and context-dependent cell-cell or cell-environment interaction. Because of the current technical limitation, obtaining genome-wide spatial transcriptome at single-cell resolution is challenging. Her...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Chao, Chen, Renchao, Zhang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417177/ https://www.ncbi.nlm.nih.gov/pubmed/36026447 http://dx.doi.org/10.1126/sciadv.abq0990

Ejemplares similares

Cell composition inference and identification of layer-specific spatial transcriptional profiles with POLARIS
por: Chen, Jiawen, et al.
Publicado: (2023)

Comprehensive analysis of spatial architecture in primary liver cancer
por: Wu, Rui, et al.
Publicado: (2021)

Cellular-scale proximity labeling for recording cell spatial organization in mouse tissues
por: Zhang, Xu, et al.
Publicado: (2023)

Spatial resolution of an integrated C(4)+CAM photosynthetic metabolism
por: Moreno-Villena, Jose J., et al.
Publicado: (2022)

Hierarchical self-uncloaking CRISPR-Cas13a–customized RNA nanococoons for spatial-controlled genome editing and precise cancer therapy
por: Fan, Ningke, et al.
Publicado: (2022)

RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis
por: Zhang, Shu, et al.
Publicado: (2021)

Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors
por: Smith, Cheryl L., et al.
Publicado: (2021)

Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function
por: Román-Fernández, Alvaro, et al.
Publicado: (2023)

Single-cell and spatial transcriptome analysis reveals the cellular heterogeneity of liver metastatic colorectal cancer
por: Wang, Fei, et al.
Publicado: (2023)

TATTOO-seq delineates spatial and cell type–specific regulatory programs in the developing limb
por: Bastide, Sébastien, et al.
Publicado: (2022)

Spatial and temporal regulation of Wnt signaling pathway members in the development of butterfly wing patterns
por: Banerjee, Tirtha Das, et al.
Publicado: (2023)

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis
por: Coulis, Gerald, et al.
Publicado: (2023)

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
por: Feng, Xu, et al.
Publicado: (2022)

Spatially targeted brain cancer immunotherapy with closed-loop controlled focused ultrasound and immune checkpoint blockade
por: Lee, Hohyun, et al.
Publicado: (2022)

Digital spatial profiling of intraductal papillary mucinous neoplasms: Toward a molecular framework for risk stratification
por: Iyer, Matthew K., et al.
Publicado: (2023)

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium
por: Song, Daniel, et al.
Publicado: (2022)

Spatial interplay patterns of cancer nuclei and tumor-infiltrating lymphocytes (TILs) predict clinical benefit for immune checkpoint inhibitors
por: Wang, Xiangxue, et al.
Publicado: (2022)

Genome-wide gain-of-function screening characterized lncRNA regulators for tumor immune response
por: Wang, Yifei, et al.
Publicado: (2022)

Cosegregation of recombinant chromatids maintains genome-wide heterozygosity in an asexual nematode
por: Blanc, Caroline, et al.
Publicado: (2023)

Preferred synonymous codons are translated more accurately: Proteomic evidence, among-species variation, and mechanistic basis
por: Sun, Mengyi, et al.
Publicado: (2022)

Genome-wide association studies identify the role of caspase-9 in kidney disease
por: Doke, Tomohito, et al.
Publicado: (2021)

Genome-wide CRISPR screens define determinants of epithelial-mesenchymal transition mediated immune evasion by pancreatic cancer cells
por: Gu, Yuanzhuo, et al.
Publicado: (2023)

Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways
por: Yu, Zhi, et al.
Publicado: (2022)

RNase H genes cause distinct impacts on RNA:DNA hybrid formation and mutagenesis genome wide
por: Schroeder, Jeremy W., et al.
Publicado: (2023)

Coordinated DNA and histone dynamics drive accurate histone H2A.Z exchange
por: Poyton, Matthew F., et al.
Publicado: (2022)

The extinct shark Otodus megalodon was a transoceanic superpredator: Inferences from 3D modeling
por: Cooper, Jack A., et al.
Publicado: (2022)

Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naïve pluripotent cell reprogramming
por: Collier, Amanda J., et al.
Publicado: (2022)

Genomic imprinting-like monoallelic paternal expression determines sex of channel catfish
por: Wang, Wenwen, et al.
Publicado: (2022)

Comprehensive analysis and accurate quantification of unintended large gene modifications induced by CRISPR-Cas9 gene editing
por: Park, So Hyun, et al.
Publicado: (2022)

Accurate detection of benign and malignant renal tumor subtypes with MethylBoostER: An epigenetic marker–driven learning framework
por: Rossi, Sabrina H., et al.
Publicado: (2022)

DNA replication initiation shapes the mutational landscape and expression of the human genome
por: Murat, Pierre, et al.
Publicado: (2022)

Accurate prediction of HLA class II antigen presentation across all loci using tailored data acquisition and refined machine learning
por: Nilsson, Jonas B., et al.
Publicado: (2023)

Essential autoproteolysis of bacterial anti-σ factor RsgI for transmembrane signal transduction
por: Chen, Chao, et al.
Publicado: (2023)

Thermostable ionizable lipid-like nanoparticle (iLAND) for RNAi treatment of hyperlipidemia
por: Hu, Bo, et al.
Publicado: (2022)

Promotion of row 1–specific tip complex condensates by Gpsm2-Gαi provides insights into row identity of the tallest stereocilia
por: Shi, Yingdong, et al.
Publicado: (2022)

LATS1 is a central signal transmitter for achieving full type-I interferon activity
por: Zuo, Yibo, et al.
Publicado: (2022)

VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation
por: Hu, Zhiqiang, et al.
Publicado: (2023)

Deubiquitination of proteasome subunits by OTULIN regulates type I IFN production
por: Tao, Panfeng, et al.
Publicado: (2021)

PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling
por: Gao, Shaoyan, et al.
Publicado: (2022)

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases
por: Moreno-Yruela, Carlos, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mbtdrult9eo9ceblavqsjb66gu