Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury

Altered host-microbe interactions and increased intestinal permeability have been implicated in disease pathogenesis. However, the mechanisms by which intestinal microbes affect epithelial barrier integrity remain unclear. Here, we investigate the impact of bacterial metabolism of host-produced bile...

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Detalles Bibliográficos
Autores principales: Li, Darrick K., Chaudhari, Snehal N., Lee, Yoojin, Sojoodi, Mozhdeh, Adhikari, Arijit A., Zukerberg, Lawrence, Shroff, Stuti, Barrett, Stephen Cole, Tanabe, Kenneth, Chung, Raymond T., Devlin, A. Sloan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417178/
https://www.ncbi.nlm.nih.gov/pubmed/36026454
http://dx.doi.org/10.1126/sciadv.abo2794

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