Regulation of microglial activation in stroke in aged mice: a translational study

Numerous neurochemical changes occur with aging and stroke mainly affects the elderly. Our previous study has found interferon regulatory factor 5 (IRF5) and 4 (IRF4) regulate neuroinflammation in young stroke mice. However, whether the IRF5-IRF4 regulatory axis has the same effect in aged brains is...

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Detalles Bibliográficos
Autores principales: Ngwa, Conelius, Al Mamun, Abdullah, Qi, Shaohua, Sharmeen, Romana, Xu, Yan, Liu, Fudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417226/
https://www.ncbi.nlm.nih.gov/pubmed/35963621
http://dx.doi.org/10.18632/aging.204216