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Polymer conjugated graphene-oxide nanoparticles impair nuclear DNA and Topoisomerase I in cancer

Cancer chemotherapy had been dominated by the use of small molecule DNA damaging drugs. Eventually, the emergence of DNA damage repair machinery in cancer cells has led to combination therapy with the DNA topology controlling enzyme, topoisomerase I inhibitor along with DNA impairing agents. However...

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Detalles Bibliográficos
Autores principales:	Nandi, Aditi, Ghosh, Chandramouli, Basu, Sudipta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417292/ https://www.ncbi.nlm.nih.gov/pubmed/36133106 http://dx.doi.org/10.1039/c9na00617f

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