Multisystem Inflammatory Syndrome in an Adult Who Received Casirivimab-Imdevimab (REGEN-COV)

Multisystem inflammatory syndrome in adults (MIS-A) is a systemic inflammatory syndrome that presents with a heterogeneous collection of signs and symptoms in adults. Here we present a case of a 38-year-old male who met the case definition of the MIS-A four weeks after a mild, symptomatic case of co...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Gurdeep, Osman, Alsayed, Ryad, Robert, Nguyen, Phuong, Itzkowitz, Raphael, Maharam, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Allergy/Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417327/
https://www.ncbi.nlm.nih.gov/pubmed/36046289
http://dx.doi.org/10.7759/cureus.27353
_version_ 1784776688031236096
author Singh, Gurdeep
Osman, Alsayed
Ryad, Robert
Nguyen, Phuong
Itzkowitz, Raphael
Maharam, Edward
author_facet Singh, Gurdeep
Osman, Alsayed
Ryad, Robert
Nguyen, Phuong
Itzkowitz, Raphael
Maharam, Edward
author_sort Singh, Gurdeep
collection PubMed
description Multisystem inflammatory syndrome in adults (MIS-A) is a systemic inflammatory syndrome that presents with a heterogeneous collection of signs and symptoms in adults. Here we present a case of a 38-year-old male who met the case definition of the MIS-A four weeks after a mild, symptomatic case of coronavirus disease 2019 (COVID-19) despite receiving casirivimab-imdevimab (REGEN-COV). Given the presence of signs and symptoms consistent with MIS-A, the patient was started on intravenous immune globulin (IVIG) and IV methylprednisolone. He promptly demonstrated clinical improvement over the next several days. 
format Online
Article
Text
id pubmed-9417327
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-94173272022-08-30 Multisystem Inflammatory Syndrome in an Adult Who Received Casirivimab-Imdevimab (REGEN-COV) Singh, Gurdeep Osman, Alsayed Ryad, Robert Nguyen, Phuong Itzkowitz, Raphael Maharam, Edward Cureus Allergy/Immunology Multisystem inflammatory syndrome in adults (MIS-A) is a systemic inflammatory syndrome that presents with a heterogeneous collection of signs and symptoms in adults. Here we present a case of a 38-year-old male who met the case definition of the MIS-A four weeks after a mild, symptomatic case of coronavirus disease 2019 (COVID-19) despite receiving casirivimab-imdevimab (REGEN-COV). Given the presence of signs and symptoms consistent with MIS-A, the patient was started on intravenous immune globulin (IVIG) and IV methylprednisolone. He promptly demonstrated clinical improvement over the next several days.  Cureus 2022-07-27 /pmc/articles/PMC9417327/ /pubmed/36046289 http://dx.doi.org/10.7759/cureus.27353 Text en Copyright © 2022, Singh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Allergy/Immunology
Singh, Gurdeep
Osman, Alsayed
Ryad, Robert
Nguyen, Phuong
Itzkowitz, Raphael
Maharam, Edward
Multisystem Inflammatory Syndrome in an Adult Who Received Casirivimab-Imdevimab (REGEN-COV)
title Multisystem Inflammatory Syndrome in an Adult Who Received Casirivimab-Imdevimab (REGEN-COV)
title_full Multisystem Inflammatory Syndrome in an Adult Who Received Casirivimab-Imdevimab (REGEN-COV)
title_fullStr Multisystem Inflammatory Syndrome in an Adult Who Received Casirivimab-Imdevimab (REGEN-COV)
title_full_unstemmed Multisystem Inflammatory Syndrome in an Adult Who Received Casirivimab-Imdevimab (REGEN-COV)
title_short Multisystem Inflammatory Syndrome in an Adult Who Received Casirivimab-Imdevimab (REGEN-COV)
title_sort multisystem inflammatory syndrome in an adult who received casirivimab-imdevimab (regen-cov)
topic Allergy/Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417327/
https://www.ncbi.nlm.nih.gov/pubmed/36046289
http://dx.doi.org/10.7759/cureus.27353
work_keys_str_mv AT singhgurdeep multisysteminflammatorysyndromeinanadultwhoreceivedcasirivimabimdevimabregencov
AT osmanalsayed multisysteminflammatorysyndromeinanadultwhoreceivedcasirivimabimdevimabregencov
AT ryadrobert multisysteminflammatorysyndromeinanadultwhoreceivedcasirivimabimdevimabregencov
AT nguyenphuong multisysteminflammatorysyndromeinanadultwhoreceivedcasirivimabimdevimabregencov
AT itzkowitzraphael multisysteminflammatorysyndromeinanadultwhoreceivedcasirivimabimdevimabregencov
AT maharamedward multisysteminflammatorysyndromeinanadultwhoreceivedcasirivimabimdevimabregencov

Ejemplares similares