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The state of the art of extracellular vesicle research in protozoan infection
Protozoan diseases seriously affect the health of human beings, livestock and poultry and lead to high economic and medical costs. Extracellular vesicles (EVs) are membranous structures formed through biological processes that play important roles in immune regulation. Studies have shown that parasi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417467/ https://www.ncbi.nlm.nih.gov/pubmed/36035188 http://dx.doi.org/10.3389/fgene.2022.941561 |
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author | Wang, Xinlei Chen, Jie Zheng, Jingtong |
author_facet | Wang, Xinlei Chen, Jie Zheng, Jingtong |
author_sort | Wang, Xinlei |
collection | PubMed |
description | Protozoan diseases seriously affect the health of human beings, livestock and poultry and lead to high economic and medical costs. Extracellular vesicles (EVs) are membranous structures formed through biological processes that play important roles in immune regulation. Studies have shown that parasites transmit information to hosts through EVs to modulate host immune responses. The major roles played by EVs released from parasites involve facilitating parasitization of the host. In this review, we discuss relevant recently obtained data on EVs secreted by different kinds of protozoa, including their molecular mechanisms, and discuss the roles played by EVs in the occurrence and development of parasitic diseases. |
format | Online Article Text |
id | pubmed-9417467 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94174672022-08-27 The state of the art of extracellular vesicle research in protozoan infection Wang, Xinlei Chen, Jie Zheng, Jingtong Front Genet Genetics Protozoan diseases seriously affect the health of human beings, livestock and poultry and lead to high economic and medical costs. Extracellular vesicles (EVs) are membranous structures formed through biological processes that play important roles in immune regulation. Studies have shown that parasites transmit information to hosts through EVs to modulate host immune responses. The major roles played by EVs released from parasites involve facilitating parasitization of the host. In this review, we discuss relevant recently obtained data on EVs secreted by different kinds of protozoa, including their molecular mechanisms, and discuss the roles played by EVs in the occurrence and development of parasitic diseases. Frontiers Media S.A. 2022-08-12 /pmc/articles/PMC9417467/ /pubmed/36035188 http://dx.doi.org/10.3389/fgene.2022.941561 Text en Copyright © 2022 Wang, Chen and Zheng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics Wang, Xinlei Chen, Jie Zheng, Jingtong The state of the art of extracellular vesicle research in protozoan infection |
title | The state of the art of extracellular vesicle research in protozoan infection |
title_full | The state of the art of extracellular vesicle research in protozoan infection |
title_fullStr | The state of the art of extracellular vesicle research in protozoan infection |
title_full_unstemmed | The state of the art of extracellular vesicle research in protozoan infection |
title_short | The state of the art of extracellular vesicle research in protozoan infection |
title_sort | state of the art of extracellular vesicle research in protozoan infection |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417467/ https://www.ncbi.nlm.nih.gov/pubmed/36035188 http://dx.doi.org/10.3389/fgene.2022.941561 |
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