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The state of the art of extracellular vesicle research in protozoan infection

Protozoan diseases seriously affect the health of human beings, livestock and poultry and lead to high economic and medical costs. Extracellular vesicles (EVs) are membranous structures formed through biological processes that play important roles in immune regulation. Studies have shown that parasi...

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Detalles Bibliográficos
Autores principales: Wang, Xinlei, Chen, Jie, Zheng, Jingtong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417467/
https://www.ncbi.nlm.nih.gov/pubmed/36035188
http://dx.doi.org/10.3389/fgene.2022.941561
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author Wang, Xinlei
Chen, Jie
Zheng, Jingtong
author_facet Wang, Xinlei
Chen, Jie
Zheng, Jingtong
author_sort Wang, Xinlei
collection PubMed
description Protozoan diseases seriously affect the health of human beings, livestock and poultry and lead to high economic and medical costs. Extracellular vesicles (EVs) are membranous structures formed through biological processes that play important roles in immune regulation. Studies have shown that parasites transmit information to hosts through EVs to modulate host immune responses. The major roles played by EVs released from parasites involve facilitating parasitization of the host. In this review, we discuss relevant recently obtained data on EVs secreted by different kinds of protozoa, including their molecular mechanisms, and discuss the roles played by EVs in the occurrence and development of parasitic diseases.
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spelling pubmed-94174672022-08-27 The state of the art of extracellular vesicle research in protozoan infection Wang, Xinlei Chen, Jie Zheng, Jingtong Front Genet Genetics Protozoan diseases seriously affect the health of human beings, livestock and poultry and lead to high economic and medical costs. Extracellular vesicles (EVs) are membranous structures formed through biological processes that play important roles in immune regulation. Studies have shown that parasites transmit information to hosts through EVs to modulate host immune responses. The major roles played by EVs released from parasites involve facilitating parasitization of the host. In this review, we discuss relevant recently obtained data on EVs secreted by different kinds of protozoa, including their molecular mechanisms, and discuss the roles played by EVs in the occurrence and development of parasitic diseases. Frontiers Media S.A. 2022-08-12 /pmc/articles/PMC9417467/ /pubmed/36035188 http://dx.doi.org/10.3389/fgene.2022.941561 Text en Copyright © 2022 Wang, Chen and Zheng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Wang, Xinlei
Chen, Jie
Zheng, Jingtong
The state of the art of extracellular vesicle research in protozoan infection
title The state of the art of extracellular vesicle research in protozoan infection
title_full The state of the art of extracellular vesicle research in protozoan infection
title_fullStr The state of the art of extracellular vesicle research in protozoan infection
title_full_unstemmed The state of the art of extracellular vesicle research in protozoan infection
title_short The state of the art of extracellular vesicle research in protozoan infection
title_sort state of the art of extracellular vesicle research in protozoan infection
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417467/
https://www.ncbi.nlm.nih.gov/pubmed/36035188
http://dx.doi.org/10.3389/fgene.2022.941561
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