Stem cell-derived exosomal transcriptomes for wound healing

Wound healing is a complex and integrated process of the interaction of various components within the injured tissue. Accumulating evidence suggested that stem cell-derived exosomal transcriptomes could serve as key regulatory molecules in wound healing in stem cell therapy. Stem cell-derived exosom...

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Detalles Bibliográficos
Autores principales: Chen, Guiling, Chen, Hankun, Zeng, Xiang, Zhu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417542/
https://www.ncbi.nlm.nih.gov/pubmed/36034367
http://dx.doi.org/10.3389/fsurg.2022.933781
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author Chen, Guiling
Chen, Hankun
Zeng, Xiang
Zhu, Wei
author_facet Chen, Guiling
Chen, Hankun
Zeng, Xiang
Zhu, Wei
author_sort Chen, Guiling
collection PubMed
description Wound healing is a complex and integrated process of the interaction of various components within the injured tissue. Accumulating evidence suggested that stem cell-derived exosomal transcriptomes could serve as key regulatory molecules in wound healing in stem cell therapy. Stem cell-derived exosomal transcriptomes mainly consist of long noncoding RNAs (lncRNAs), microRNAs (miRNAs), circular RNAs (circRNAs) and messenger RNAs (mRNAs). In this article we presented a brief introduction on the wound repair process and exosomal transcriptomes. Meanwhile, we summarized our current knowledge of the involvement of exosomal transcriptomes in physiological and pathological wound repair process including inflammation, angiogenesis, and scar formation.
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spelling pubmed-94175422022-08-27 Stem cell-derived exosomal transcriptomes for wound healing Chen, Guiling Chen, Hankun Zeng, Xiang Zhu, Wei Front Surg Surgery Wound healing is a complex and integrated process of the interaction of various components within the injured tissue. Accumulating evidence suggested that stem cell-derived exosomal transcriptomes could serve as key regulatory molecules in wound healing in stem cell therapy. Stem cell-derived exosomal transcriptomes mainly consist of long noncoding RNAs (lncRNAs), microRNAs (miRNAs), circular RNAs (circRNAs) and messenger RNAs (mRNAs). In this article we presented a brief introduction on the wound repair process and exosomal transcriptomes. Meanwhile, we summarized our current knowledge of the involvement of exosomal transcriptomes in physiological and pathological wound repair process including inflammation, angiogenesis, and scar formation. Frontiers Media S.A. 2022-08-12 /pmc/articles/PMC9417542/ /pubmed/36034367 http://dx.doi.org/10.3389/fsurg.2022.933781 Text en © 2022 Chen, Chen, Zeng and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Chen, Guiling
Chen, Hankun
Zeng, Xiang
Zhu, Wei
Stem cell-derived exosomal transcriptomes for wound healing
title Stem cell-derived exosomal transcriptomes for wound healing
title_full Stem cell-derived exosomal transcriptomes for wound healing
title_fullStr Stem cell-derived exosomal transcriptomes for wound healing
title_full_unstemmed Stem cell-derived exosomal transcriptomes for wound healing
title_short Stem cell-derived exosomal transcriptomes for wound healing
title_sort stem cell-derived exosomal transcriptomes for wound healing
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417542/
https://www.ncbi.nlm.nih.gov/pubmed/36034367
http://dx.doi.org/10.3389/fsurg.2022.933781
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AT chenhankun stemcellderivedexosomaltranscriptomesforwoundhealing
AT zengxiang stemcellderivedexosomaltranscriptomesforwoundhealing
AT zhuwei stemcellderivedexosomaltranscriptomesforwoundhealing

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