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Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells

Fluorescent nanoparticles (NPs) comprising polyethylene terephthalate (PET) with a hydrodynamic diameter of 158 ± 2 nm were synthesized in a bottom-up approach. Concentration-dependent uptake and cytotoxicity of PET NPs in macrophages are shown. The fabrication of well-characterized NPs, derived fro...

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Autores principales: Johnson, Leah M., Mecham, Jeffrey B., Krovi, Sai Archana, Moreno Caffaro, Maria M., Aravamudhan, Shyam, Kovach, Alexander L., Fennell, Timothy R., Mortensen, Ninell P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417664/
https://www.ncbi.nlm.nih.gov/pubmed/36131728
http://dx.doi.org/10.1039/d0na00888e
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author Johnson, Leah M.
Mecham, Jeffrey B.
Krovi, Sai Archana
Moreno Caffaro, Maria M.
Aravamudhan, Shyam
Kovach, Alexander L.
Fennell, Timothy R.
Mortensen, Ninell P.
author_facet Johnson, Leah M.
Mecham, Jeffrey B.
Krovi, Sai Archana
Moreno Caffaro, Maria M.
Aravamudhan, Shyam
Kovach, Alexander L.
Fennell, Timothy R.
Mortensen, Ninell P.
author_sort Johnson, Leah M.
collection PubMed
description Fluorescent nanoparticles (NPs) comprising polyethylene terephthalate (PET) with a hydrodynamic diameter of 158 ± 2 nm were synthesized in a bottom-up approach. Concentration-dependent uptake and cytotoxicity of PET NPs in macrophages are shown. The fabrication of well-characterized NPs, derived from high-commodity polymers, will support future studies to assess effects on biological systems.
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spelling pubmed-94176642022-09-20 Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells Johnson, Leah M. Mecham, Jeffrey B. Krovi, Sai Archana Moreno Caffaro, Maria M. Aravamudhan, Shyam Kovach, Alexander L. Fennell, Timothy R. Mortensen, Ninell P. Nanoscale Adv Chemistry Fluorescent nanoparticles (NPs) comprising polyethylene terephthalate (PET) with a hydrodynamic diameter of 158 ± 2 nm were synthesized in a bottom-up approach. Concentration-dependent uptake and cytotoxicity of PET NPs in macrophages are shown. The fabrication of well-characterized NPs, derived from high-commodity polymers, will support future studies to assess effects on biological systems. RSC 2020-12-15 /pmc/articles/PMC9417664/ /pubmed/36131728 http://dx.doi.org/10.1039/d0na00888e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Johnson, Leah M.
Mecham, Jeffrey B.
Krovi, Sai Archana
Moreno Caffaro, Maria M.
Aravamudhan, Shyam
Kovach, Alexander L.
Fennell, Timothy R.
Mortensen, Ninell P.
Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells
title Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells
title_full Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells
title_fullStr Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells
title_full_unstemmed Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells
title_short Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells
title_sort fabrication of polyethylene terephthalate (pet) nanoparticles with fluorescent tracers for studies in mammalian cells
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417664/
https://www.ncbi.nlm.nih.gov/pubmed/36131728
http://dx.doi.org/10.1039/d0na00888e
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