Cargando…

Inhibition of the m(6)A reader IGF2BP2 as a strategy against T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignant leukemia with extremely limited treatment for relapsed patients. N6‐methyladenosine (m(6)A) reader insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) participates in the initiation and growth of cancers by communicatin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Panpan, Chen, Dawei, Wang, Xia, Li, Yanxia, Li, Zhenyu, Li, Boya, Zhang, Yupeng, Li, Wei, Zhang, Jingru, Ye, Jingjing, Zhao, Baobing, Li, Jingxin, Ji, Chunyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417996/ https://www.ncbi.nlm.nih.gov/pubmed/35915142 http://dx.doi.org/10.1038/s41375-022-01651-9

Ejemplares similares

The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
por: Wang, Xia, et al.
Publicado: (2021)

The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability
por: Zhang, Nan, et al.
Publicado: (2022)

IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader
por: Hu, Xiaoge, et al.
Publicado: (2019)

IGF2BP3 Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia
por: Mäkinen, Artturi, et al.
Publicado: (2021)

Identification of the function and mechanism of m6A reader IGF2BP2 in Alzheimer’s disease
por: Deng, Yanyao, et al.
Publicado: (2021)

N(6)-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma
por: Zheng, Xin, et al.
Publicado: (2023)

IGF2BP2 Regulates MALAT1 by Serving as an N6-Methyladenosine Reader to Promote NSCLC Proliferation
por: Han, Le, et al.
Publicado: (2022)

N(6)-methyladenosine (m(6)A) reader IGF2BP2 promotes gastric cancer progression via targeting SIRT1
por: Zhang, Zili, et al.
Publicado: (2022)

The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers
por: Wang, Jinyan, et al.
Publicado: (2021)

m(6)A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma
por: Fang, Han, et al.
Publicado: (2023)

Reply to the Comment on “The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ”
por: Wang, Xia, et al.
Publicado: (2022)

Silencing of IRF8 Mediated by m6A Modification Promotes the Progression of T‐Cell Acute Lymphoblastic Leukemia
por: Zhou, Ying, et al.
Publicado: (2022)

RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation
por: Zhu, Kai, et al.
Publicado: (2023)

Identification of Two m6A Readers YTHDF1 and IGF2BP2 as Immune Biomarkers in Head and Neck Squamous Cell Carcinoma
por: Li, Shaojie, et al.
Publicado: (2022)

An oncopeptide regulates m(6)A recognition by the m(6)A reader IGF2BP1 and tumorigenesis
por: Zhu, Song, et al.
Publicado: (2020)

MYC-activated RNA N6-methyladenosine reader IGF2BP3 promotes cell proliferation and metastasis in nasopharyngeal carcinoma
por: Du, Mingyu, et al.
Publicado: (2022)

RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA
por: Fan, Jin, et al.
Publicado: (2023)

m(6)A reader IGF2BP2-stabilized CASC9 accelerates glioblastoma aerobic glycolysis by enhancing HK2 mRNA stability
por: Liu, Hongjiang, et al.
Publicado: (2021)

Multi-omics analysis of N6-methyladenosine reader IGF2BP3 as a promising biomarker in pan-cancer
por: Chen, Pin, et al.
Publicado: (2023)

m6A Reader Igf2bp1 Regulates the Inflammatory Responses of Microglia by Stabilizing Gbp11 and Cp mRNAs
por: Ding, Lu, et al.
Publicado: (2022)

Clinical Significance of an m6A Reader Gene, IGF2BP2, in Head and Neck Squamous Cell Carcinoma
por: Deng, Xiaoli, et al.
Publicado: (2020)

Novel gene signature reveals prognostic model in acute lymphoblastic leukemia
por: Chen, Panpan, et al.
Publicado: (2022)

RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer
por: Yang, Zhou, et al.
Publicado: (2020)

Role of IGF2BP3 in trophoblast cell invasion and migration
por: Li, W, et al.
Publicado: (2014)

Targeting IGF2BP3 in Cancer
por: Liu, Xin, et al.
Publicado: (2023)

Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2
por: Yang, Yang, et al.
Publicado: (2020)

Diagnostic Utility of IGF2BP1 and Its Targets as Potential Biomarkers in ETV6-RUNX1 Positive B-Cell Acute Lymphoblastic Leukemia
por: Sharma, Gunjan, et al.
Publicado: (2021)

RNA binding protein IGF2BP1 synergizes with ETV6-RUNX1 to drive oncogenic signaling in B-cell Acute Lymphoblastic Leukemia
por: Sharma, Gunjan, et al.
Publicado: (2023)

Transfer of IGF2BP3 Through Ara-C-Induced Apoptotic Bodies Promotes Survival of Recipient Cells
por: Gou, Junjie, et al.
Publicado: (2022)

Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer
por: Sun, Xin, et al.
Publicado: (2023)

Knockdown of m6A Reader IGF2BP3 Inhibited Hypoxia-Induced Cell Migration and Angiogenesis by Regulating Hypoxia Inducible Factor-1α in Stomach Cancer
por: Jiang, Libin, et al.
Publicado: (2021)

Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
por: Schymik, Hanna S., et al.
Publicado: (2022)

EGR2-mediated regulation of m(6)A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization
por: Ying, Yufan, et al.
Publicado: (2021)

Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD(+) AML Cells
por: Feng, Panpan, et al.
Publicado: (2022)

N(6)-methyladenosine (m(6)A) reader IGF2BP1 facilitates clear-cell renal cell carcinoma aerobic glycolysis
por: Yuan, Bao, et al.
Publicado: (2023)

The m6A reader IGF2BP3 preserves NOTCH3 mRNA stability to sustain Notch3 signaling and promote tumor metastasis in nasopharyngeal carcinoma
por: Chen, Boyu, et al.
Publicado: (2023)

RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression
por: Regué, Laura, et al.
Publicado: (2021)

m(6)A reader IGF2BP1 accelerates apoptosis of high glucose-induced vascular endothelial cells in a m(6)A-HMGB1 dependent manner
por: Liang, Anru, et al.
Publicado: (2023)

LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma
por: Liu, Yihao, et al.
Publicado: (2022)

Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA
por: Pan, Xiaojuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tpdj5nrlafr5q1jh67u5t20dl9