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Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys
The SARS-CoV-2 Omicron variant has very high levels of transmission, is resistant to neutralization by authorized therapeutic human monoclonal antibodies (mAb) and is less sensitive to vaccine-mediated immunity. To provide additional therapies against Omicron, we isolated a mAb named P2G3 from a pre...
Autores principales: | Fenwick, Craig, Turelli, Priscilla, Ni, Dongchun, Perez, Laurent, Lau, Kelvin, Herate, Cécile, Marlin, Romain, Lana, Erica, Pellaton, Céline, Raclot, Charlène, Esteves-Leuenberger, Line, Campos, Jérémy, Farina, Alex, Fiscalini, Flurin, Dereuddre-Bosquet, Nathalie, Relouzat, Francis, Abdelnabi, Rana, Foo, Caroline S., Neyts, Johan, Leyssen, Pieter, Lévy, Yves, Pojer, Florence, Stahlberg, Henning, LeGrand, Roger, Trono, Didier, Pantaleo, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418005/ https://www.ncbi.nlm.nih.gov/pubmed/35879526 http://dx.doi.org/10.1038/s41564-022-01198-6 |
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