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Sex‐bias in CD8 (+) T‐cell stemness and exhaustion in cancer

This commentary article highlights two recently published studies, which for the first time revealed the immunological underpinnings of sex‐bias in cancer incidence and mortality. These studies showed that the androgen receptor restrains anti‐tumour immunity in males by repressing cytotoxic genes in...

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Detalles Bibliográficos
Autores principales: Hussain, Tabinda, Kallies, Axel, Vasanthakumar, Ajithkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418121/
https://www.ncbi.nlm.nih.gov/pubmed/36051310
http://dx.doi.org/10.1002/cti2.1414