Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse

Signaling by the human C-type lectin-like receptor, natural killer (NK) cell inhibitory receptor NKR-P1, has a critical role in many immune-related diseases and cancer. C-type lectin-like receptors have weak affinities to their ligands; therefore, setting up a comprehensive model of NKR-P1-LLT1 inte...

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Detalles Bibliográficos
Autores principales: Bláha, Jan, Skálová, Tereza, Kalousková, Barbora, Skořepa, Ondřej, Cmunt, Denis, Grobárová, Valéria, Pazicky, Samuel, Poláchová, Edita, Abreu, Celeste, Stránský, Jan, Kovaľ, Tomáš, Dušková, Jarmila, Zhao, Yuguang, Harlos, Karl, Hašek, Jindřich, Dohnálek, Jan, Vaněk, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418145/
https://www.ncbi.nlm.nih.gov/pubmed/36028489
http://dx.doi.org/10.1038/s41467-022-32577-6

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