Paving the way to improve therapy for Myeloproliferative Neoplasms

Long-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that media...

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Detalles Bibliográficos
Autores principales: Bywater, Megan, Lane, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418146/
https://www.ncbi.nlm.nih.gov/pubmed/36028499
http://dx.doi.org/10.1038/s41467-022-32694-2
Descripción
Sumario:Long-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that mediate treatment resistance.

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