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Ammonia promotes the proliferation of bone marrow-derived mesenchymal stem cells by regulating the Akt/mTOR/S6k pathway

Ammonia plays an important role in cellular metabolism. However, ammonia is considered a toxic product. In bone marrow-derived mesenchymal stem cells, multipotent stem cells with high expression of glutamine synthetase (GS) in bone marrow, ammonia and glutamate can be converted to glutamine via glut...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Zhang, Xiangxian, Wang, Wei, Liu, Ting, Ren, Jun, Chen, Siyuan, Lu, Tianqi, Tie, Yan, Yuan, Xia, Mo, Fei, Yang, Jingyun, Wei, Yuquan, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418171/
https://www.ncbi.nlm.nih.gov/pubmed/36028500
http://dx.doi.org/10.1038/s41413-022-00215-y