Cargando…

Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI

Animal models are an indispensable platform used in various research disciplines, enabling, for example, studies of basic biological mechanisms, pathological processes and new therapeutic interventions. In this study, we applied magnetic resonance imaging (MRI) to characterize the clinical picture o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kraiger, Markus, Klein-Rodewald, Tanja, Rathkolb, Birgit, Calzada-Wack, Julia, Sanz-Moreno, Adrián, Fuchs, Helmut, Wolf, Eckhard, Gailus-Durner, Valérie, de Angelis, Martin Hrabě
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418174/ https://www.ncbi.nlm.nih.gov/pubmed/36028522 http://dx.doi.org/10.1038/s41598-022-17880-y

Ejemplares similares

New C3H Kit(N824K/WT) cancer mouse model develops late-onset malignant mammary tumors with high penetrance
por: Klein-Rodewald, Tanja, et al.
Publicado: (2022)

Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction
por: Milenkovic, Dusanka, et al.
Publicado: (2022)

Uromodulin Retention in Thick Ascending Limb of Henle's Loop Affects SCD1 in Neighboring Proximal Tubule: Renal Transcriptome Studies in Mouse Models of Uromodulin-Associated Kidney Disease
por: Horsch, Marion, et al.
Publicado: (2014)

Knockout mouse models as a resource for the study of rare diseases
por: da Silva-Buttkus, Patricia, et al.
Publicado: (2023)

Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality
por: Sluka, Susanna H. M., et al.
Publicado: (2019)

Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk
por: Garrett, Lillian, et al.
Publicado: (2022)

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression
por: Kaklamanos, Aimilios, et al.
Publicado: (2017)

Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments
por: Zumbrennen-Bullough, Kimberly B., et al.
Publicado: (2014)

Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1(I27N) mutant mice
por: Kumar, Sudhir, et al.
Publicado: (2017)

A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse
por: Biagosch, Caroline A., et al.
Publicado: (2021)

MausDB: An open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects
por: Maier, Holger, et al.
Publicado: (2008)

Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse
por: Müller-Eigner, Annika, et al.
Publicado: (2022)

Mechanisms Controlling Anaemia in Trypanosoma congolense Infected Mice
por: Noyes, Harry A., et al.
Publicado: (2009)

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells
por: Raab, Monika, et al.
Publicado: (2011)

Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon
por: Puk, Oliver, et al.
Publicado: (2013)

Mouse Nuclear Myosin I Knock-Out Shows Interchangeability and Redundancy of Myosin Isoforms in the Cell Nucleus
por: Venit, Tomáš, et al.
Publicado: (2013)

METTL6 is a tRNA m(3)C methyltransferase that regulates pluripotency and tumor cell growth
por: Ignatova, Valentina V., et al.
Publicado: (2020)

Knockout mice are an important tool for human monogenic heart disease studies
por: Cacheiro, Pilar, et al.
Publicado: (2023)

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription
por: Brina, Daniela, et al.
Publicado: (2015)

Peroxidasin is essential for eye development in the mouse
por: Yan, Xiaohe, et al.
Publicado: (2014)

Defective immuno- and thymoproteasome assembly causes severe immunodeficiency
por: Treise, Irina, et al.
Publicado: (2018)

Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction
por: Spielmann, Nadine, et al.
Publicado: (2022)

Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma
por: Aguilar-Pimentel, Antonio, et al.
Publicado: (2017)

Correction: The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers
por: Pozzi, Benedetta, et al.
Publicado: (2013)

The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers
por: Pozzi, Benedetta, et al.
Publicado: (2012)

A rationale for considering heart/brain axis control in neuropsychiatric disease
por: Garrett, Lillian, et al.
Publicado: (2022)

The rRNA m(6)A methyltransferase METTL5 is involved in pluripotency and developmental programs
por: Ignatova, Valentina V., et al.
Publicado: (2020)

Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets
por: Götz, Alexander A, et al.
Publicado: (2011)

Meis1: effects on motor phenotypes and the sensorimotor system in mice
por: Salminen, Aaro V., et al.
Publicado: (2017)

Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria
por: Lucienne, Marie, et al.
Publicado: (2023)

RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation
por: Bartsch, Kareen, et al.
Publicado: (2018)

New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis
por: Sabrautzki, Sibylle, et al.
Publicado: (2012)

Erratum to: New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis
por: Sabrautzki, Sibylle, et al.
Publicado: (2014)

Standardized, Systemic Phenotypic Analysis of Umod (C93F) and Umod (A227T) Mutant Mice
por: Kemter, Elisabeth, et al.
Publicado: (2013)

Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification
por: Santos, Maria C. Ferreira dos, et al.
Publicado: (2020)

A robust and reliable non-invasive test for stress responsivity in mice
por: Zimprich, Annemarie, et al.
Publicado: (2014)

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes
por: Kollmus, Heike, et al.
Publicado: (2020)

N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels
por: Aigner, Bernhard, et al.
Publicado: (2009)

Dll1 Haploinsufficiency in Adult Mice Leads to a Complex Phenotype Affecting Metabolic and Immunological Processes
por: Rubio-Aliaga, Isabel, et al.
Publicado: (2009)

Standardized, systemic phenotypic analysis of Slc12a1(I299F) mutant mice
por: Kemter, Elisabeth, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7trbsllhu2ohmog0rrvdapbp6b