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PERM1 regulates genes involved in fatty acid metabolism in the heart by interacting with PPARα and PGC-1α

PERM1 (PGC-1/ERR-induced regulator in muscle 1) is a muscle-specific protein induced by PGC-1 and ERRs. Previous studies have shown that PERM1 promotes mitochondrial biogenesis and metabolism in cardiomyocytes in vitro. However, the role of endogenous PERM1 in the heart remains to be investigated wi...

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Detalles Bibliográficos
Autores principales:	Huang, Chun-yang, Oka, Shin-ichi, Xu, Xiaoyong, Chen, Chian-Feng, Tung, Chien-Yi, Chang, Ya-Yuan, Mourad, Youssef, Vehra, Omair, Ivessa, Andreas, Yehia, Ghassan, Romanienko, Peter, Hsu, Chiao-Po, Sadoshima, Junichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418182/ https://www.ncbi.nlm.nih.gov/pubmed/36028747 http://dx.doi.org/10.1038/s41598-022-18885-3

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