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Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model

Cancer is clearly a major cause of disease and fatality around the world, yet little is known about how it starts and spreads. In this study, a model in mathematical form of breast cancer guided by a system of (ODE’S) ordinary differential equations is studied in depth to examine the thermal effects...

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Autores principales: Dolat Khan, Rahman, Ata ur, Kumam, Poom, Watthayu, Wiboonsak, Sitthithakerngkiet, Kanokwan, Galal, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418218/
https://www.ncbi.nlm.nih.gov/pubmed/36039134
http://dx.doi.org/10.1016/j.heliyon.2022.e10170
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author Dolat Khan
Rahman, Ata ur
Kumam, Poom
Watthayu, Wiboonsak
Sitthithakerngkiet, Kanokwan
Galal, Ahmed M.
author_facet Dolat Khan
Rahman, Ata ur
Kumam, Poom
Watthayu, Wiboonsak
Sitthithakerngkiet, Kanokwan
Galal, Ahmed M.
author_sort Dolat Khan
collection PubMed
description Cancer is clearly a major cause of disease and fatality around the world, yet little is known about how it starts and spreads. In this study, a model in mathematical form of breast cancer guided by a system of (ODE’S) ordinary differential equations is studied in depth to examine the thermal effects of various shape nanoparticles on breast cancer hyperthermia therapy in the existence of a porous media with fractional derivative connection, when utilizing microwave radiative heating. The unsteady state is determined precisely using the Laplace transform approach to crop a more decisive examination of temperature dissemination of blood temperature inside the breast tissues. Durbin's and Zakian's techniques are used to find Laplace inversion. Mild temperature hyperthermia is used in the treatment, which promotes cell death by increasing cell nervousness to radiation therapy and flow of blood in tumor. In the graphical findings, we can witness the distinct behavior of hyperthermia therapy on tumor cells by applying various metabolic heat generation rates across various time intervals to attain the optimal therapeutic temperature point. Particularly, we used graphs to visualize the behavior of different Nanoparticles with different shaped during hypothermia therapy. In comparison to other nanoparticles and shapes, it demonstrates that gold nanoparticles with a platelet shape are the best option for improving heat transmission. Which assess of heat transfer up to 16.412%.
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spelling pubmed-94182182022-08-28 Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model Dolat Khan Rahman, Ata ur Kumam, Poom Watthayu, Wiboonsak Sitthithakerngkiet, Kanokwan Galal, Ahmed M. Heliyon Research Article Cancer is clearly a major cause of disease and fatality around the world, yet little is known about how it starts and spreads. In this study, a model in mathematical form of breast cancer guided by a system of (ODE’S) ordinary differential equations is studied in depth to examine the thermal effects of various shape nanoparticles on breast cancer hyperthermia therapy in the existence of a porous media with fractional derivative connection, when utilizing microwave radiative heating. The unsteady state is determined precisely using the Laplace transform approach to crop a more decisive examination of temperature dissemination of blood temperature inside the breast tissues. Durbin's and Zakian's techniques are used to find Laplace inversion. Mild temperature hyperthermia is used in the treatment, which promotes cell death by increasing cell nervousness to radiation therapy and flow of blood in tumor. In the graphical findings, we can witness the distinct behavior of hyperthermia therapy on tumor cells by applying various metabolic heat generation rates across various time intervals to attain the optimal therapeutic temperature point. Particularly, we used graphs to visualize the behavior of different Nanoparticles with different shaped during hypothermia therapy. In comparison to other nanoparticles and shapes, it demonstrates that gold nanoparticles with a platelet shape are the best option for improving heat transmission. Which assess of heat transfer up to 16.412%. Elsevier 2022-08-11 /pmc/articles/PMC9418218/ /pubmed/36039134 http://dx.doi.org/10.1016/j.heliyon.2022.e10170 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Article
Dolat Khan
Rahman, Ata ur
Kumam, Poom
Watthayu, Wiboonsak
Sitthithakerngkiet, Kanokwan
Galal, Ahmed M.
Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model
title Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model
title_full Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model
title_fullStr Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model
title_full_unstemmed Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model
title_short Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model
title_sort thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: a fractional model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418218/
https://www.ncbi.nlm.nih.gov/pubmed/36039134
http://dx.doi.org/10.1016/j.heliyon.2022.e10170
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