Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis

In pneumococcal meningitis, bacterial growth in the cerebrospinal fluid results in lysis, the release of toxic factors, and subsequent neuroinflammation. Exposure of primary murine glia to Streptococcus pneumoniae lysates leads to strong proinflammatory cytokine and chemokine production, blocked by...

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Detalles Bibliográficos
Autores principales: Hupp, Sabrina, Förtsch, Christina, Graber, Franziska, Mitchell, Timothy J., Iliev, Asparouh I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418233/
https://www.ncbi.nlm.nih.gov/pubmed/36028511
http://dx.doi.org/10.1038/s41467-022-32624-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418233/
https://www.ncbi.nlm.nih.gov/pubmed/36028511
http://dx.doi.org/10.1038/s41467-022-32624-2

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