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Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis
In pneumococcal meningitis, bacterial growth in the cerebrospinal fluid results in lysis, the release of toxic factors, and subsequent neuroinflammation. Exposure of primary murine glia to Streptococcus pneumoniae lysates leads to strong proinflammatory cytokine and chemokine production, blocked by...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418233/ https://www.ncbi.nlm.nih.gov/pubmed/36028511 http://dx.doi.org/10.1038/s41467-022-32624-2 |