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The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation
The signaling adaptor MAVS forms prion-like aggregates to activate the innate antiviral immune response after viral infection. However, spontaneous aggregation of MAVS can lead to autoimmune diseases. The molecular mechanism that prevents MAVS from spontaneous aggregation in resting cells has been e...
Autores principales: | Bai, Xuemei, Sui, Chao, Liu, Feng, Chen, Tian, Zhang, Lei, Zheng, Yi, Liu, Bingyu, Gao, Chengjiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418238/ https://www.ncbi.nlm.nih.gov/pubmed/36028484 http://dx.doi.org/10.1038/s41467-022-32628-y |
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