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The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation

The signaling adaptor MAVS forms prion-like aggregates to activate the innate antiviral immune response after viral infection. However, spontaneous aggregation of MAVS can lead to autoimmune diseases. The molecular mechanism that prevents MAVS from spontaneous aggregation in resting cells has been e...

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Detalles Bibliográficos
Autores principales: Bai, Xuemei, Sui, Chao, Liu, Feng, Chen, Tian, Zhang, Lei, Zheng, Yi, Liu, Bingyu, Gao, Chengjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418238/
https://www.ncbi.nlm.nih.gov/pubmed/36028484
http://dx.doi.org/10.1038/s41467-022-32628-y

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