Astroglial Knockout of Glucocorticoid Receptor Attenuates Morphine Withdrawal Symptoms, but Not Antinociception and Tolerance in Mice

The development of tolerance and drug dependence limit the clinical application of opioids for the treatment of severe pain. Glucocorticoid receptors (GRs) are among molecular substrates involved in these processes. Most studies focus on the role of neuronal GR, while the involvement of GR on glial...

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Detalles Bibliográficos
Autores principales: Tertil, Magdalena, Skupio, Urszula, Kudla, Lucja, Wiktorowska, Lucja, Przewlocki, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418269/
https://www.ncbi.nlm.nih.gov/pubmed/33821329
http://dx.doi.org/10.1007/s10571-021-01086-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418269/
https://www.ncbi.nlm.nih.gov/pubmed/33821329
http://dx.doi.org/10.1007/s10571-021-01086-3

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