Studies of mutations of assembly factor Hit1 in budding yeast suggest translation defects as the molecular basis for PEHO syndrome

Regulation of protein synthesis is critical for control of gene expression in all cells. Ribosomes are ribonucleoprotein machines responsible for translating cellular proteins. Defects in ribosome production, function, or regulation are detrimental to the cell and cause human diseases, such as progr...

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Detalles Bibliográficos
Autores principales: Dreggors-Walker, R. Elizabeth, Cohen, Lauren N., Khoshnevis, Sohail, Marchand, Virginie, Motorin, Yuri, Ghalei, Homa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418376/
https://www.ncbi.nlm.nih.gov/pubmed/35843310
http://dx.doi.org/10.1016/j.jbc.2022.102261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418376/
https://www.ncbi.nlm.nih.gov/pubmed/35843310
http://dx.doi.org/10.1016/j.jbc.2022.102261

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