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Biodistribution and dosimetry of the GluN2B-specific NMDA receptor PET radioligand (R)-[(11)C]Me-NB1

BACKGROUND: The NMDA receptor (NMDAR) plays a key role in the central nervous system, e.g., for synaptic transmission. While synaptic NMDARs are thought to have protective characteristics, activation of extrasynaptic NMDARs might trigger excitotoxic processes linked to neuropsychiatric disorders. Si...

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Detalles Bibliográficos
Autores principales:	Rischka, Lucas, Murgaš, Matej, Pichler, Verena, Vraka, Chrysoula, Rausch, Ivo, Winkler, Dietmar, Nics, Lukas, Rasul, Sazan, Silberbauer, Leo Robert, Reed, Murray Bruce, Godbersen, Godber Mathis, Unterholzner, Jakob, Handschuh, Patricia, Gryglewski, Gregor, Mindt, Thomas, Mitterhauser, Markus, Hahn, Andreas, Ametamey, Simon Mensah, Wadsak, Wolfgang, Lanzenberger, Rupert, Hacker, Marcus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418393/ https://www.ncbi.nlm.nih.gov/pubmed/36018389 http://dx.doi.org/10.1186/s13550-022-00925-8

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