Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial

BACKGROUND: Diabetic peripheral neuropathic pain (DPNP) is common and often distressing. Most guidelines recommend amitriptyline, duloxetine, pregabalin, or gabapentin as initial analgesic treatment for DPNP, but there is little comparative evidence on which one is best or whether they should be com...

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Detalles Bibliográficos
Autores principales: Tesfaye, Solomon, Sloan, Gordon, Petrie, Jennifer, White, David, Bradburn, Mike, Julious, Stephen, Rajbhandari, Satyan, Sharma, Sanjeev, Rayman, Gerry, Gouni, Ravikanth, Alam, Uazman, Cooper, Cindy, Loban, Amanda, Sutherland, Katie, Glover, Rachel, Waterhouse, Simon, Turton, Emily, Horspool, Michelle, Gandhi, Rajiv, Maguire, Deirdre, Jude, Edward B, Ahmed, Syed H, Vas, Prashanth, Hariman, Christian, McDougall, Claire, Devers, Marion, Tsatlidis, Vasileios, Johnson, Martin, Rice, Andrew S C, Bouhassira, Didier, Bennett, David L, Selvarajah, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418415/
https://www.ncbi.nlm.nih.gov/pubmed/36007534
http://dx.doi.org/10.1016/S0140-6736(22)01472-6

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