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RNA binding by ADAR3 inhibits adenosine-to-inosine editing and promotes expression of immune response protein MAVS

Members of the ADAR family of double-stranded RNA–binding proteins regulate one of the most abundant RNA modifications in humans, the deamination of adenosine to inosine. Several transcriptome-wide studies have been carried out to identify RNA targets of the active deaminases ADAR1 and ADAR2. Howeve...

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Detalles Bibliográficos
Autores principales:	Raghava Kurup, Reshma, Oakes, Eimile K., Manning, Aidan C., Mukherjee, Priyanka, Vadlamani, Pranathi, Hundley, Heather A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418441/ https://www.ncbi.nlm.nih.gov/pubmed/35850307 http://dx.doi.org/10.1016/j.jbc.2022.102267

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