Cargando…
The oxidoreductase CLIC4 is required to maintain mitochondrial function and resistance to exogenous oxidants in breast cancer cells
The chloride intracellular channel-4 (CLIC4) is one of the six highly conserved proteins in the CLIC family that share high structural homology with GST-omega in the GST superfamily. While CLIC4 is a multifunctional protein that resides in multiple cellular compartments, the discovery of its enzymat...
Autores principales: | Al Khamici, Heba, Sanchez, Vanesa C., Yan, Hualong, Cataisson, Christophe, Michalowski, Aleksandra M., Yang, Howard H., Li, Luowei, Lee, Maxwell P., Huang, Jing, Yuspa, Stuart H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418444/ https://www.ncbi.nlm.nih.gov/pubmed/35863434 http://dx.doi.org/10.1016/j.jbc.2022.102275 |
Ejemplares similares
-
Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4
por: Carofino, Brandi L., et al.
Publicado: (2019) -
Elevating CLIC4 in Multiple Cell Types Reveals a TGF-β Dependent Induction of a Dominant Negative Smad7 Splice Variant
por: Shukla, Anjali, et al.
Publicado: (2016) -
TGF-β signalling is regulated by Schnurri-2 dependent nuclear translocation of CLIC4 and consequent stabilization of phospho Smad2–3
por: Shukla, Anjali, et al.
Publicado: (2009) -
Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence
por: Sanchez, Vanesa C., et al.
Publicado: (2022) -
Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity
por: Hernandez-Fernaud, Juan R., et al.
Publicado: (2017)