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Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation

MicroRNA-124a (miR-124a) is one of the most abundantly expressed microRNAs in the central nervous system and is encoded in mammals by the three genomic loci miR-124a-1/2/3; however, its in vivo roles in neuronal development and function remain ambiguous. In the present study, we investigated the eff...

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Detalles Bibliográficos
Autores principales: Chaya, Taro, Maeda, Yamato, Sugimura, Ryo, Okuzaki, Daisuke, Watanabe, Satoshi, Varner, Leah R., Motooka, Daisuke, Gyoten, Daichi, Yamamoto, Haruka, Kato, Hidemasa, Furukawa, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418502/
https://www.ncbi.nlm.nih.gov/pubmed/35868558
http://dx.doi.org/10.1016/j.jbc.2022.102293