Cargando…

Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study

BACKGROUND: Differences in survival between groups may reflect avoidable and modifiable inequalities. This study examines the 35-year mortality risk for adults aged 25–44 years in the mid-1980s with disability due to vision, hearing, or motor impairment; physical illness; or mental health problems....

Descripción completa

Detalles Bibliográficos
Autores principales: Langballe, Ellen Melbye, Tangen, Gro Gujord, Engdahl, Bo, Strand, Bjørn Heine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418547/
https://www.ncbi.nlm.nih.gov/pubmed/36039147
http://dx.doi.org/10.1016/j.lanepe.2022.100482
_version_ 1784776970584719360
author Langballe, Ellen Melbye
Tangen, Gro Gujord
Engdahl, Bo
Strand, Bjørn Heine
author_facet Langballe, Ellen Melbye
Tangen, Gro Gujord
Engdahl, Bo
Strand, Bjørn Heine
author_sort Langballe, Ellen Melbye
collection PubMed
description BACKGROUND: Differences in survival between groups may reflect avoidable and modifiable inequalities. This study examines the 35-year mortality risk for adults aged 25–44 years in the mid-1980s with disability due to vision, hearing, or motor impairment; physical illness; or mental health problems. METHODS: This Norwegian study was based on data from the Trøndelag Health Study (HUNT1, 1984–86, and HUNT2, 1995–97) linked to tax-registry data for deaths before 15 November 2019. Mortality risk was estimated by Cox regression analysis adjusted for age and sex. Sensitivity analysis included the following possible mediators: education, work, living situation, body mass index, systolic blood pressure and smoking. FINDINGS: Of the 30,080 HUNT1 participants aged 25–44 years, 5071 (16.9%) reported having disability. During the 35 years of follow-up, 1069 (21.1%) participants with disability and 3107 (12.4%) without disability died. Individuals with any type of disability had 62% higher mortality risk compared to those without a disability, adjusted by age and sex. The highest mortality risks were observed for disability due to severe motor impairment (HR=3.67, 95%CI=2.89–4.67) and severe mental health problems (HR=3.40, 95%CI=2.75–4.23) compared to those without these disabilities. Increased mortality risk was found for all the included disability types. The associations were somewhat mediated, especially by education, work and living situation. INTERPRETATION: This study shows that among adults aged 25–44 years, the risk of death increases with disability of different types and severity levels, particularly for disability related to mental health problems or motor impairment. FUNDING: None.
format Online
Article
Text
id pubmed-9418547
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-94185472022-08-28 Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study Langballe, Ellen Melbye Tangen, Gro Gujord Engdahl, Bo Strand, Bjørn Heine Lancet Reg Health Eur Articles BACKGROUND: Differences in survival between groups may reflect avoidable and modifiable inequalities. This study examines the 35-year mortality risk for adults aged 25–44 years in the mid-1980s with disability due to vision, hearing, or motor impairment; physical illness; or mental health problems. METHODS: This Norwegian study was based on data from the Trøndelag Health Study (HUNT1, 1984–86, and HUNT2, 1995–97) linked to tax-registry data for deaths before 15 November 2019. Mortality risk was estimated by Cox regression analysis adjusted for age and sex. Sensitivity analysis included the following possible mediators: education, work, living situation, body mass index, systolic blood pressure and smoking. FINDINGS: Of the 30,080 HUNT1 participants aged 25–44 years, 5071 (16.9%) reported having disability. During the 35 years of follow-up, 1069 (21.1%) participants with disability and 3107 (12.4%) without disability died. Individuals with any type of disability had 62% higher mortality risk compared to those without a disability, adjusted by age and sex. The highest mortality risks were observed for disability due to severe motor impairment (HR=3.67, 95%CI=2.89–4.67) and severe mental health problems (HR=3.40, 95%CI=2.75–4.23) compared to those without these disabilities. Increased mortality risk was found for all the included disability types. The associations were somewhat mediated, especially by education, work and living situation. INTERPRETATION: This study shows that among adults aged 25–44 years, the risk of death increases with disability of different types and severity levels, particularly for disability related to mental health problems or motor impairment. FUNDING: None. Elsevier 2022-08-19 /pmc/articles/PMC9418547/ /pubmed/36039147 http://dx.doi.org/10.1016/j.lanepe.2022.100482 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Articles
Langballe, Ellen Melbye
Tangen, Gro Gujord
Engdahl, Bo
Strand, Bjørn Heine
Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study
title Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study
title_full Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study
title_fullStr Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study
title_full_unstemmed Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study
title_short Increased mortality risk for adults aged 25–44 years with long-term disability: A prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based HUNT study
title_sort increased mortality risk for adults aged 25–44 years with long-term disability: a prospective cohort study with a 35-year follow-up of 30,080 individuals from 1984–2019 in the population-based hunt study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418547/
https://www.ncbi.nlm.nih.gov/pubmed/36039147
http://dx.doi.org/10.1016/j.lanepe.2022.100482
work_keys_str_mv AT langballeellenmelbye increasedmortalityriskforadultsaged2544yearswithlongtermdisabilityaprospectivecohortstudywitha35yearfollowupof30080individualsfrom19842019inthepopulationbasedhuntstudy
AT tangengrogujord increasedmortalityriskforadultsaged2544yearswithlongtermdisabilityaprospectivecohortstudywitha35yearfollowupof30080individualsfrom19842019inthepopulationbasedhuntstudy
AT engdahlbo increasedmortalityriskforadultsaged2544yearswithlongtermdisabilityaprospectivecohortstudywitha35yearfollowupof30080individualsfrom19842019inthepopulationbasedhuntstudy
AT strandbjørnheine increasedmortalityriskforadultsaged2544yearswithlongtermdisabilityaprospectivecohortstudywitha35yearfollowupof30080individualsfrom19842019inthepopulationbasedhuntstudy