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Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites

BACKGROUND: Plasmodium falciparum (Pf) sporozoite (SPZ) vaccines are the only candidate malaria vaccines that induce > 90% vaccine efficacy (VE) against controlled human malaria infection and the only malaria vaccines to have achieved reproducible VE against malaria in adults in Africa. The goal...

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Detalles Bibliográficos
Autores principales: Chakravarty, Sumana, Shears, Melanie J., James, Eric R., Rai, Urvashi, KC, Natasha, Conteh, Solomon, Lambert, Lynn E., Duffy, Patrick E., Murphy, Sean C., Hoffman, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418655/
https://www.ncbi.nlm.nih.gov/pubmed/36030292
http://dx.doi.org/10.1186/s12936-022-04261-z