Computational design and characterization of a multiepitope vaccine against carbapenemase-producing Klebsiella pneumoniae strains, derived from antigens identified through reverse vaccinology

Klebsiella pneumoniae is a Gram-negative pathogen of clinical relevance, which can provoke serious urinary and blood infections and pneumonia. This bacterium is a major public health threat due to its resistance to several antibiotic classes. Using a reverse vaccinology approach, 7 potential antigen...

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Detalles Bibliográficos
Autores principales: Cuscino, Nicola, Fatima, Ayesha, Di Pilato, Vincenzo, Bulati, Matteo, Alfano, Caterina, Monaca, Elisa, Di Mento, Giuseppina, Di Carlo, Daniele, Cardinale, Francesca, Monaco, Francesco, Rossolini, Gian Maria, Khan, Asif M., Conaldi, Pier Giulio, Douradinha, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418682/
https://www.ncbi.nlm.nih.gov/pubmed/36051872
http://dx.doi.org/10.1016/j.csbj.2022.08.035

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