Single-cell transcriptomics of neuroblastoma identifies chemoresistance-associated genes and pathways

High-Risk neuroblastoma (NB) survival rate is still <50%, despite treatments being more and more aggressive. The biggest hurdle liable to cancer therapy failure is the drug resistance by tumor cells that is likely due to the intra-tumor heterogeneity (ITH). To investigate the link between ITH and...

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Detalles Bibliográficos
Autores principales: Avitabile, Marianna, Bonfiglio, Ferdinando, Aievola, Vincenzo, Cantalupo, Sueva, Maiorino, Teresa, Lasorsa, Vito Alessandro, Domenicotti, Cinzia, Marengo, Barbara, Zbyněk, Heger, Vojtěch, Adam, Iolascon, Achille, Capasso, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418686/
https://www.ncbi.nlm.nih.gov/pubmed/36051886
http://dx.doi.org/10.1016/j.csbj.2022.08.031

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