A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity

The homeostatic mechanisms that fail to restrain chronic tissue inflammation in diseases, such as psoriasis vulgaris, remain incompletely understood. We profiled transcriptomes and epitopes of single psoriatic and normal skin-resident T cells, revealing a gradated transcriptional program of coordina...

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Detalles Bibliográficos
Autores principales: Cook, Christopher P., Taylor, Mark, Liu, Yale, Schmidt, Ralf, Sedgewick, Andrew, Kim, Esther, Hailer, Ashley, North, Jeffrey P., Harirchian, Paymann, Wang, Hao, Kashem, Sakeen W., Shou, Yanhong, McCalmont, Timothy C., Benz, Stephen C., Choi, Jaehyuk, Purdom, Elizabeth, Marson, Alexander, Ramos, Silvia B.V., Cheng, Jeffrey B., Cho, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418858/
https://www.ncbi.nlm.nih.gov/pubmed/35977472
http://dx.doi.org/10.1016/j.xcrm.2022.100715

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