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mTORC1 is required for epigenetic silencing during β-cell functional maturation

OBJECTIVE: The mechanistic target of rapamycin complex 1 (mTORC1) is a key molecule that links nutrients, hormones, and growth factors to cell growth/function. Our previous studies have shown that mTORC1 is required for β-cell functional maturation and identity maintenance; however, the underlying m...

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Detalles Bibliográficos
Autores principales:	Ni, Qicheng, Sun, Jiajun, Wang, Yichen, Wang, Yanqiu, Liu, Jingwen, Ning, Guang, Wang, Weiqing, Wang, Qidi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9418906/ https://www.ncbi.nlm.nih.gov/pubmed/35940555 http://dx.doi.org/10.1016/j.molmet.2022.101559

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