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Outcome of COVID-19 in Children With Tuberculosis: Single-Center Experience

OBJECTIVE: To evaluate the outcome of Coronavirus disease 2019 (COVID-19) infection in children and adolescents with tuberculosis. METHODS: We analyzed hospital records for the period May, 2020 to September, 2021 for children who were severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reve...

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Autores principales: Mane, Sushant S., Janardhanan, Jyothi, Pustake, Manas, Wanvat, Akshay, Khan, Gazi Israil, Chopade, Rajratna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419137/
https://www.ncbi.nlm.nih.gov/pubmed/35962655
http://dx.doi.org/10.1007/s13312-022-2574-6
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author Mane, Sushant S.
Janardhanan, Jyothi
Pustake, Manas
Wanvat, Akshay
Khan, Gazi Israil
Chopade, Rajratna
author_facet Mane, Sushant S.
Janardhanan, Jyothi
Pustake, Manas
Wanvat, Akshay
Khan, Gazi Israil
Chopade, Rajratna
author_sort Mane, Sushant S.
collection PubMed
description OBJECTIVE: To evaluate the outcome of Coronavirus disease 2019 (COVID-19) infection in children and adolescents with tuberculosis. METHODS: We analyzed hospital records for the period May, 2020 to September, 2021 for children who were severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcriptase-polymerase chain reaction (RT-PCR) positive or SARS-CoV-2 antibody positive. They were divided into two groups viz., those with tuberculosis (tuberculosis group) and those without tuberculosis (non-TB group). Demographic information, symptoms, and outcomes of COVID-19 were compared between the two groups. RESULTS: Median (IQR) age of participants was 11 (8,14) and 4.5 (2,9) year for the tuberculosis and non-TB groups, respectively. 93.5% and 36.1% of children were asymptomatic in the tuberculosis and non-TB group, respectively. No variable in the study was significantly associated with COVID-19 positivity in children with tuberculosis. No difference was found in the outcomes of COVID-19 infection in children having tuberculosis. CONCLUSIONS: No differences were noted in the outcomes of COVID-19 infection in children having tuberculosis.
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spelling pubmed-94191372022-08-30 Outcome of COVID-19 in Children With Tuberculosis: Single-Center Experience Mane, Sushant S. Janardhanan, Jyothi Pustake, Manas Wanvat, Akshay Khan, Gazi Israil Chopade, Rajratna Indian Pediatr Research Paper OBJECTIVE: To evaluate the outcome of Coronavirus disease 2019 (COVID-19) infection in children and adolescents with tuberculosis. METHODS: We analyzed hospital records for the period May, 2020 to September, 2021 for children who were severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcriptase-polymerase chain reaction (RT-PCR) positive or SARS-CoV-2 antibody positive. They were divided into two groups viz., those with tuberculosis (tuberculosis group) and those without tuberculosis (non-TB group). Demographic information, symptoms, and outcomes of COVID-19 were compared between the two groups. RESULTS: Median (IQR) age of participants was 11 (8,14) and 4.5 (2,9) year for the tuberculosis and non-TB groups, respectively. 93.5% and 36.1% of children were asymptomatic in the tuberculosis and non-TB group, respectively. No variable in the study was significantly associated with COVID-19 positivity in children with tuberculosis. No difference was found in the outcomes of COVID-19 infection in children having tuberculosis. CONCLUSIONS: No differences were noted in the outcomes of COVID-19 infection in children having tuberculosis. Springer India 2022-08-27 2022 /pmc/articles/PMC9419137/ /pubmed/35962655 http://dx.doi.org/10.1007/s13312-022-2574-6 Text en © Indian Academy of Pediatrics 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Paper
Mane, Sushant S.
Janardhanan, Jyothi
Pustake, Manas
Wanvat, Akshay
Khan, Gazi Israil
Chopade, Rajratna
Outcome of COVID-19 in Children With Tuberculosis: Single-Center Experience
title Outcome of COVID-19 in Children With Tuberculosis: Single-Center Experience
title_full Outcome of COVID-19 in Children With Tuberculosis: Single-Center Experience
title_fullStr Outcome of COVID-19 in Children With Tuberculosis: Single-Center Experience
title_full_unstemmed Outcome of COVID-19 in Children With Tuberculosis: Single-Center Experience
title_short Outcome of COVID-19 in Children With Tuberculosis: Single-Center Experience
title_sort outcome of covid-19 in children with tuberculosis: single-center experience
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419137/
https://www.ncbi.nlm.nih.gov/pubmed/35962655
http://dx.doi.org/10.1007/s13312-022-2574-6
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