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Placental imprinting of SLC22A3 in the IGF2R imprinted domain is conserved in therian mammals

BACKGROUND: The eutherian IGF2R imprinted domain is regulated by an antisense long non-coding RNA, Airn, which is expressed from a differentially methylated region (DMR) in mice. Airn silences two neighbouring genes, Solute carrier family 22 member 2 (Slc22a2) and Slc22a3, to establish the Igf2r imp...

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Detalles Bibliográficos
Autores principales: Ishihara, Teruhito, Griffith, Oliver W., Suzuki, Shunsuke, Renfree, Marilyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419357/
https://www.ncbi.nlm.nih.gov/pubmed/36030241
http://dx.doi.org/10.1186/s13072-022-00465-4

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